Remeron is an effective drug that is prescribed to treat depressive, anxious, and mixed disorders and which is often used in psychotherapeutic and neurological practice. The drug is a unique antidepressant of a new generation of tetracyclic series, as it affects histamine receptors, which is not typical for medications of this group. It also has a sedative effect.
Structure of the medicine
The product is produced in tablet form. The active component of Remeron is mirtazapine. Depending on the dosage, each tablet contains 45 mg, 30 mg, or 15 mg of the active substance.
The drug eliminates the symptoms of depression, reduces anxiety and aggressiveness, and improves mood. The medication removes irritability, dysphoria, and obsessive thoughts. It also has a pronounced soothing and anxiolytic effect. Remeron is useful in the treatment of anxiety disorders and depressive states of different genesis. An antidepressant effect is observed after one to two weeks of therapy.
Indications and contraindications
Remeron is effective in the following diseases and disorders: insomnia, depressive state, bipolar affective disorder, anhedonia, inhibited psychomotor reactions, apathy, anxiety disorder, and suicidal behavior.
The manufacturer’s instructions indicate that Remeron has the following contraindications: lactase deficiency, pathology of the liver, hypersensitivity to substances, kidney failure, and intolerance to lactase.
The drug is prescribed with caution in patients with closed-angle glaucoma, epileptic seizures, atrial fibrillation, diabetes mellitus, hypotension, acute myocardial infarction, prostatic hypertrophy, and/or organic brain lesions.
Dosage and route of administration
The medication is prescribed as an initial dose of 15 mg per day. Gradually, the dosage may be increased to 45 mg. It is recommended to take the medicine once a day in the evening.
The duration of treatment lasts from four to six months, until the clinical symptoms begin to disappear. However, if no improvement is observed after two months, the therapy should be stopped. Withdrawal symptoms are possible in the case of a sharp recusal of the medication.
Possible side effects may occur during treatment with Remeron, including:
- Digestive system: vomiting, excess weight, dryness in the oral cavity, soreness in the abdomen, nausea, and increased appetite
- Central nervous system: tremor of extremities, hallucinations, dizziness, headache, drowsiness, and hyperkinesis
- Hematopoietic system: agranulocytosis, thrombocytopenia, neutropenia, aplastic anemia, and eosinophilia
- Shortness of breath, muscle pain, swelling, and lowering of blood pressure
It is important to keep in mind that Remeron increases psychotic symptoms in individuals who have schizophrenia.
Additionally, patients whose profession is associated with the management of complex mechanisms should be careful when taking Remeron.
Elderly patients should take the drug with caution and under the supervision of a specialist.
The drug is not allowed to be used by pregnant women or in case of lactation, since the active substance can penetrate into the breast milk.
It is not allowed to be used as a medicine in children.
Remeron in combination with alcohol increases the depressive state.